Talk:Designer baby

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Potential Edits[edit]

This group will be adding information to the pre-existing sections of the article. We will be including additional subheadings to ensure the article remains organized. Our focus is on the medical process, gene editing techniques, regulation of PGD, germline modification, aspects of genetics, gene therapy, the statistical significance of each technique, genetic diseases that can be cured using these techniques, and the ethics behind germline modification. Lefereol (talk) 02:46, 1 November 2016 (UTC)

Vandalism[edit]

For some reason I fail to grasp, of the 100 articles I watch over, Designer baby is the article that attracts the most (juvenile) vandalism. How can we stop this once and for all? --Loremaster (talk) 04:02, 21 October 2009 (UTC)

Factual Accuracy[edit]

Preimplantation genetic diagnosis section: There is a difference between embryo screening for genetic defects and making a designer baby by selecting physical features. This article needs to differentiate between the two procedures. Furthermore, the article explains that pre-implantation genetic diagnosis is a procedure done before fertilization, but it does not describe what is done to the embryos. Also, there are major pieces missing about the process of artificial reproduction technology (ART), like in-vitro fertilization. The article explains that a baby could be created to avoid diseases and select for desired traits, but did not explain the medical process behind it very well. Lefereol (talk) 13:43, 26 October 2016 (UTC)


The claims in this article, although they have a reference, are based on opinion and not fact, and lack a neutral point of view. I suggest these parts be re-edited. http://en.wikipedia.org/wiki/Wikipedia:Neutral_point_of_view JonatasM (talk) 04:31, 30 July 2010 (UTC)

Putting aside that an encyclopedic article can contain opinions as long as they come from reliable sources, I hadn't noticed that the article has been re-written so much that its sounds like a bioconversative leaftet. It should defenitely be re-written. --Loremaster (talk) 16:59, 30 July 2010 (UTC)

If someone makes the article long enough, maybe vandels would not understand it and quit vandalizing it. —Preceding unsigned comment added by 69.237.148.156 (talk) 23:39, 5 October 2010 (UTC)

The following statements are misleading: 1)"Genetic modification can be used to alter anything from gender to disease, and eventually appearance, personality, and even IQ."

It is not currently possible to modify the human genetic code to alter gender, appearance, personality or IQ. Not one single case of this has ever been reported.

2) "Altering embryos is fairly recent technology and as it develops is a very costly procedure."

The term "altering" is misleading. An embryo can be tested for presence of a genetic trait (disease) and then a decision can be made to NOT use or implant that embryo. If the genetic trait or mutation is present, you cannot alter, change, or modify it in the embryo. —Preceding unsigned comment added by 198.175.199.253 (talk) 18:07, 3 November 2010 (UTC)

Neutrality[edit]

The style of the Biological Risks section is inappropriate for Wikipedia - using "we" invites chumminess and is not the right style, isn't it? Disregard if I'm wrong, mm. I'm afraid I don't have time to do a rewrite right now. ashdenej 10:17, 21 May 2012 (UTC)

Terrible article[edit]

As far as I know, no regulatory agency on the planet allows genetic manipulation of human gametes, zygotes, or embryos. And as far as I know, no one has even applied for such a regulatory approval. But this article written as though "designer babies" - in the sense of genetically manipulated human gametes, zygotes, or embryos - are real. Insane. And to the extent it says things like " as far as the public record is concerned" it borders on conspiracy theory, which has no place on Wikipedia unless it is described as such. I will come back and edit this article to make it sane, or recommend it for deletion. Thinking.... Jytdog (talk) 03:19, 11 December 2012 (UTC)

External links modified[edit]

I have created a list of journals and a book with information pertaining to this article. These resources could greatly contribute to the content to this article.

Stankovic, B. (2011, February 8). “It’s a designer baby!” - opinions on regulation of Preimplantation genetic diagnosis by Bratislav Stankovic: SSRN. Retrieved October 9, 2016, from http://papers.ssrn.com/sol3/papers.cfm?abstract_id=1756573

Iredale, R., Longley, M., Thomas, C., & Shaw, A. (2006). What choices should we be able to make about designer babies? A citizens’ jury of young people in south wales.Health Expectations, 9(3), 207–217. doi:10.1111/j.1369-7625.2006.00387.x

Dobson, R. (2000). “Designer baby” cures sister. ,321(7268), . Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173444/

Franklin, S., & Roberts, C. (2006). Born and made: An ethnography of Preimplantation genetic diagnosis. Retrieved from https://books.google.com/books?hl=en&lr=&id=_krN8uUKGbYC&oi=fnd&pg=PR1&dq=designer+baby&ots=rCCiWXNDA1&sig=Ozj2PXnC7yjlHUREnXHI6KnP9nw#v=onepage&q=designer%20baby&f=falseIn-line Citation:(Franklin & Roberts, 2006)

Lefereol (talk) 14:28, 9 October 2016 (UTC)


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Wiki Project - Bibliography[edit]

Brownlee, Shannon. "Designer Babies." Washington Monthly 2002Googlescholar. , cosmicawareness.org/wp-content/uploads/washingtonmonthly_designer_babies.pdf. Accessed 24 Oct. 2016.

Conger, Krista. "Parents Should Be Free to Use 'Designer Baby' Technologies." Reproductive Technologies. Ed. Clay Farris Naff. Detroit: Greenhaven Press, 2007. Opposing Viewpoints. Rpt. from "As Good As It Gets?" Stanford Medicine Magazine (Summer 2006). Opposing Viewpoints in Context. Web. 24 Oct. 2016. Dobson, R. (2000). “Designer baby” cures sister. ,321(7268), . Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173444/

Franklin, S., & Roberts, C. (2006). Born and made: An ethnography of Preimplantation genetic diagnosis. Retrieved from https://books.google.com/books?hl=en&lr=&id=_krN8uUKGbYC&oi=fnd&pg=PR1&dq=designer+baby&ots=rCCiWXNDA1&sig=Ozj2PXnC7yjlHUREnXHI6KnP9nw#v=onepage&q=designer%20baby&f=falseIn-line Citation:(Franklin & Roberts, 2006)

Gordijn, B., & Chadwick, R. F. (2009). Germline genetic modification. In Medical enhancement and posthumanity (pp. 191-205). doi:10.1007/978-1-4020-8852-0_12

Hsu, P., Lander, E., & Zhang, F. (2014). Development and Applications of CRISPR-Cas9 for Genome Engineering. Cell, 157(6), 1262-1278. doi:10.1016/j.cell.2014.05.010

Iredale, R., Longley, M., Thomas, C., & Shaw, A. (2006). What choices should we be able to make about designer babies? A citizens’ jury of young people in south wales.Health Expectations, 9(3), 207–217. doi:10.1111/j.1369-7625.2006.00387.x

King, Samantha. "Designer Babies, Stem Cells, and the Market for Genetics: The Limits of the Assisted Human Reproduction Act." Canadian Journal of Communication 32.3 (2007): 613-20. ProQuest. Web. 24 Oct. 2016.

Mahoney, J. (2010). Genome Mapping and Designer Babies: Comparative Perspective. UMKC Law Review 79(2), 309-314.

Stankovic, B. (2011, February 8). “It’s a designer baby!” - opinions on regulation of Preimplantation genetic diagnosis by Bratislav Stankovic: SSRN. Retrieved October 9, 2016, from http://papers.ssrn.com/sol3/papers.cfm?abstract_id=1756573

Thornhill, A. (2004). ESHRE PGD Consortium 'Best practice guidelines for clinical preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS)' Human Reproduction, 20(1), 35-48. doi:10.1093/humrep/deh579

Walker, M. (2008). "Designer Babies" and Harm to Supernumerary Embryos. American Philosophical Quarterly,45(4), 349-364. Retrieved from http://www.jstor.org/stable/20464426

Wolf, D. P., Mitalipov, N., & Mitalipov, S. (2015). Mitochondrial Replacement Therapy in Reproductive Medicine. Trends in Molecular Medicine, 21(2), 68–76. http://doi.org/10.1016/j.molmed.2014.12.001

Lewisb29 (talk) 14:26, 24 October 2016 (UTC)

Leerich3 (talk) 04:25, 22 November 2016 (UTC)

This article has a large amount of information in the mid sections, specifically about gene modification and how the process works in practicality I think the into and the first explanation of the Designer Baby article is somewhat short and brief. Most Wikipedia articles have a larger intro section and I think this one could use the same. I felt though that some of the sections such as some of the gene ones were quite wordy and sort of lost my interest. Perhaps it is just a personal thing but some people could find it distracting. Other minor additions: “When used to screen for a specific genetic disease or for risk of getting a disease, its main advantage is that it avoids selective abortion as the method makes it highly likely that the baby will be free of the disease under consideration” This is a small point, but I’ll include it because it’s one of the first things written in the article. The above statement, which is under the “Preimplantation Genetic Diagnosis” section about seven lines down, was a bit confusing to interpret. I would break it up in order to avoid run-on sentences. I’m not sure if this was the intention, but perhaps the OP meant to put a comma after the word ‘abortion’. ie) “….avoids selective abortion; PGD makes it highly likely that the baby……” The in vitro fertilization procedure is carried out by removing one or two cells with a needle when the embryo is at the six to ten cell stage phase. This also confused me a little bit, and some further clarification could be of use. The above explanation of in vitro fertilization just doesn’t quite seem right. First off, this statement implies that PGD involves cells from an embryo. Isn’t an embryo already fertilized? Did the OP of this statement mean to indicate that PGD involves working with an embryo that had been fertilized using in vitro methods? There is already a "microchip that can test a remarkable 1,500 genetic traits at once, including heart disease, seasonal affective disorder, obesity, athletic ability, hair and eye colour, height, susceptibility to alcohol and nicotine addictions, lactose intolerance and one of several genes linked to intelligence. It is still difficult to get enough DNA for such extensive testing but the chip designer thinks this technical problem will be solved soon.[5] This little bit of information is fascinating! I think readers would be compelled to pursue more information of these microchips: how they’re used, any possible updates on further development (if you can find it), or even a closer look at the genes involved with the traits listed above.

Improvements 1) Make sure the “Techniques in Gene Therapy” section is properly cited and is free of grammatical errors. Improvements 2) Make sure the section mentioned above does not present any sort of biased opinion. The beginning of one sentence starts off with, “But the most beneficial ones are..” Be careful that there are no personal opinions in here. Improvements 3) I would try to keep a consistent time frame throughout individual section (there are a few instances where the text goes from past to present). Also, perhaps the vocabulary can be modified so that it has more of research-like feel to it. ie) offspring, as opposed to baby; using words like overwhelming, under section Regulation of Preimplantation Genetic Diagnosis might diminish the neutral tone of the article.