Talk:Downregulation and upregulation

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Inconsistency -- why is the body of the article only about insulin?[edit]

why is the body of the article only about insulin? I don't have enough expertise to fix the article, but I know that there are all sorts of other non-insulin-related instances of upregulation and downregulation, e.g., 5ht2 downregulation that occurs after treatment with certain antidepressants.PStrait (talk) 21:45, 30 June 2009 (UTC)

I second this, I'm surprised that even 5 years after someone made this point, it's still only about insulin :P. All receptors experience up/down regulation, and insulin is really the least relevant example. I'd say most people looking into receptor regulation are probably considering it from the perspective of drug addiction/tolerance, so it seems odd that dopamine, seratonin, etc aren't mentioned. I may fix this when I have time, though I have no official credentials, it would be best for a professional to write the article. LiamSP (talk) 19:32, 6 March 2013 (UTC)
I think it is mostly diabetics that are interested in this topic. As for type-1-diabetes the dosage of insulin is a daily game with up- and downregulation. The amount of insulin you need for a certain kind of food not only depends on the food itself but also on the amount of insulin you used the days before. (talk) 13:42, 5 August 2013 (UTC)

The number of a component[edit]

This makes no sense: "Downregulation is the process by which a cell decreases the number of a cellular component...." How are cellular components numbered, and what's the significance of those numbers? If it's the number of receptors or molecules that matters, that should be stated explicitly. Unfree (talk) 05:51, 21 March 2008 (UTC)

the receptor down regulation is not specific for only insulin!! —Preceding unsigned comment added by (talk) 06:11, 6 March 2009 (UTC)

Inline citations preferred to manually adding items to "references" section.[edit]

There is a good explaination available on how the {{reflist}} template can be used: Wikipedia:Referencing for beginners ... To elaborate, the way references are generally used on wikipedia, the {{reflist}} template will automatically generate the references section at the bottom of an article from the wikimarkup of supporting citations / references is placed inline next to each fact that is able to be verified by a published book, scientific journal, etc. --Kuzetsa (talk) 17:09, 10 October 2008 (UTC)

In this case, the "Inline references" section for WP:Citing sources further explains how to bring the quality up to "Good article" status. --Kuzetsa (talk) 17:37, 10 October 2008 (UTC)