Talk:Enzyme replacement therapy

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"Enzyme replacement therapy does not "treat" the underlying disease, only the symptoms." What is the treatment of the underlying disease called?

Sorry, i dont know how to wikipedia, but that line quoted above does not make sense to me too. If anything (depending on the disease) it does treat the underlying disease, specifically replacing the missing enzyme. Missing enzymes in not a symptom, "Oh doctor, my iduronate-2-sulfatase levels feel really low". What the author is trying to say is that the mutated or missing gene is not fixed and production of the protein is instead grown and then injected into the patient. Unfortunately there are currently very few successful gene therapy cases (being the only way to initiate production of the protein within the individual... and even that does not fix the original mutation unless homologous recombination is involved). —Preceding unsigned comment added by (talk) 05:25, 17 April 2009 (UTC)