Talk:Fusion protein

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Proposed merge[edit]

I think all pages discussing "chimeric proteins" or "fusion proteins" should be combined into one page, which would discuss the general principles of proteins created through the joining of genetic sequences originally coding for separate polypeptides. This would discuss the concepts currently stubbed at recombinant fusion protein and oncogene fusion protein in separate headings, as well as discussing the idea of natually occurring fusion proteins which are not oncogenes. Concepts which are relevant to all chimeric proteins, such as the modularity of protein functional domains, could be efficiently discussed if these pages were merged, and the title would be much more obvious and intuitive to link to.

There is currently a similar page at Chimera (protein), and I'm not averse to merging all of the content into that page instead, although I think fusion protein or chimeric protein are more obvious titles. The disambiguation of membrane fusion protein could be easily handled with an "otheruses" template, rather than a full disambig page. -RustavoTalk/Contribs 04:47, 21 June 2007 (UTC)

I took a look, and it seemed that the large majority of the information on those pages was redundant, so without a great deal of grace, I simply redirected the excess pages to fusion protein. – ClockworkSoul 08:43, 29 February 2008 (UTC)

Proposed XRef[edit]

I'm currently searching for names given to the inverse process: a gene function so far only found realized as one protein but where later sequences show the split situation. Would that be called "fission protein" as in [1]? Or has an alternative nomenclature been established?

Proposed Additions[edit]

I plan to add more information on therapeutic applications including: drug composition & uses, fusion of fluorescent proteins & G-protein coupled receptors. I plan to add more information on protein design including: tandem fusion, domain insertion, post-translational protein conjugation, biocatalysts, fusion constructs. I plan to add more information on fusion protein linkers properties. — Preceding unsigned comment added by Hayleyreneely (talkcontribs) 20:22, 14 February 2018 (UTC)