Talk:Infectious mononucleosis

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Strep throat.[edit]

Strep throat is another differential.

If pt. has both, it complicates treatment, antibiotics may be indicated, but "Patients with EBV infectious mononucleosis who have positive throat cultures for group A streptococci should not be treated because this represents colonization rather than infection (see Workup)." http://emedicine.medscape.com/article/222040-medication

Pathophysiology[edit]

Under the Pathophysiology header, the following sentence: "When symptoms of infectious mononucleosis have been caused by cytomegalovirus, or by adenovirus or Toxoplasma gondii (toxoplasmosis), a heterophile antibody test will test negative."

is misleading. Someone reading this might interpret this sentence as saying that toxoplasma gondii can cause infectious mononucleosis, which is just plain untrue. The language used is easy to misinterpret. Can someone please change this to reflect that toxoplasmosis can have similar symptoms to mononucleosis, but is not the same disease. Thanks.— Preceding unsigned comment added by 66.46.50.100 (talkcontribs) 14:57, 21 July 2014‎

I rephrased this as you suggested, 66.46.50.100. Thanks for speaking up. Blue Rasberry (talk) 20:20, 29 July 2014 (UTC)

Meaning of name?[edit]

I had hoped to find here some explanation of the name mononucleosis, which literally means "single" mono, "nucleus", "disease" -osis. To the best of my limited knowledge there are some specialized cells such as red blood cells with no nucleus, but I'm not aware of any type of body cells with more than a single nucleus. Thus very nearly every cell in a body contains a single nucleus - is "mononuclear".
The article Monocyte is not much help, saying Monocytes have bean-shaped nuclei that are unilobar, which makes them one of the types of mononuclear leukocytes... - but the accompanying image clearly shows two cells each with multilobar nuclei. The same lead paragraph goes on to say Monocytes are usually identified in stained smears by their large kidney shaped or notched nucleus. If anything, this sounds self-contradictory - in other words, they have two or more lobes. Perhaps what that article was meant to say was that the nuclei are multilobar, not unilobar. Still, none of this explains the "mono" part of either "mononucleosis" or "monocyte". Could it be because the multi-lobes might appear to be multiple separate nuclei, and the "mono-" prefix simply indicates that despite appearances, there is only a single nucleus? Milkunderwood (talk) 03:05, 27 June 2015 (UTC)

See response and explanation at Talk:Monocyte#Unilobar.3F. Some of that information should still be added to this Mononucleosis article. Milkunderwood (talk) 19:51, 27 June 2015 (UTC)

YouTube video[edit]

The text of the first half or so of this article has been incorporated into a recent Studio C sketch. Just thought I should notify watchers of this article. [1] Everymorning (talk) 00:19, 15 March 2016 (UTC)

JAMA[edit]

Rational Clinical Examination about this doi:10.1001/jama.2016.2111 JFW | T@lk 15:47, 13 April 2016 (UTC)