Talk:Leucine zipper

From Wikipedia, the free encyclopedia
Jump to: navigation, search
WikiProject Molecular and Cell Biology (Rated Start-class, Mid-importance)
WikiProject icon This article is within the scope of the WikiProject Molecular and Cell Biology. To participate, visit the WikiProject for more information.
Start-Class article Start  This article has been rated as Start-Class on the project's quality scale.
 Mid  This article has been rated as Mid-importance on the project's importance scale.

Leucine zipper binding to DNA???[edit]

Why is the diagram being used showing a leucine zipper motif binding to DNA? Leucine zipper motifs are known protein:protein interaction domains, not DNA binding domains. The article itself even says so. EganioTalk 04:57, 4 February 2008 (UTC)

You sure? I'm pretty sure the Glick dictionary I used for "leucine scissors" said it was DNA-binding motif too. Additionally the article does say:

These proteins [-Leucine zipper regulatory proteins-] interact with the DNA as dimers (homo- or hetero-) and are also called basic zipper proteins (bZips).

which to me says leucine zipper molecules interact with DNA. You'll note the picture doesn't have the leucine-containing zipper domain interacting with the DNA. Rather the post-zipper "arms" or "jaws" of teh scissors do.--ZayZayEM (talk) 12:45, 4 February 2008 (UTC)
OK, now I see what the diagram is representing...I was looking at it incorrectly. Sorry about that. EganioTalk 04:54, 5 February 2008 (UTC)