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Wikipedia is not a place for original research or drug evangelism. We need to stick to whatever limited facts we have lest we come off promoting. — Preceding unsigned comment added by (talk) 04:44, 28 November 2011 (UTC)

Contradictory statements[edit]

  • article claims both "lack of euphoria" and "mild euphoria" - neither is referenced to a reliable source
  • article claims "health risks are totally unknown", then goes on to describe the risks of side effects - neither is referenced to a reliable source — Preceding unsigned comment added by (talk) 10:53, 13 September 2011 (UTC)

Health risks and side effects are not the same thing, therefore this part of the article is not contradictory. There is no published data on MPA and as such, however unreliable, firsthand anecdotal experiences are the only sources available. Anareon (talk) 23:44, 8 November 2011 (UTC)

Although it does list cardiovascular problems and chest pain which could be considered a health risk. Lysergic acid diethylamide (talk) 01:37, 10 November 2011 (UTC)

References needed[edit]

I removed this tag as there are now a number of good references for this article. — Preceding unsigned comment added by Testem (talkcontribs) 08:58, 1 March 2012 (UTC)

Intermediate product in methamphetamine synthesis?[edit]

Is methiopropamine the last intermediate chemical in one meth production method? In the first episode of Breaking Bad's season 4, Walt mentions it as the chemical that is transformed into methamphetamine as the last step of his procedure. (talk) 14:31, 3 August 2012 (UTC) The compound name he mentions is either another name for MPA or another chemical, I'm not sure. (talk) 14:34, 3 August 2012 (UTC)

No, MPA would not be usable in any step of a methamphetamine synthesis. Testem (talk) 14:43, 5 August 2012 (UTC)

Contradictory info on analog status[edit]

In the intro, the article says MPA is not a functional analog of PEA or AMP. In the legality it contemplates its (structural?) analog status in the United States. By the looks of the molecule, the thiophene is more than enough to make it a structurally distinct. For example, the n,n-dimethylethylamine on scheduled DMT is not uncommon on unscheduled drugs deemed legal by the FDA. The ring structure defines the molecule more than the alkyl and other chains, as far as US law is concerned.

On an unrelated note, is there documentation on the alleged "successful prosecutions" under the FAA? I'm only aware of two FAA cases; one of which struck it down as ambiguous, the other was partially successful because the defendant proved their intent by lying to federal agents. (talk) 23:31, 20 October 2013 (UTC)

More Better English Needed, Apply Within[edit]

Beside those pathways it shoud be mentioned that two drugs containing a thiophene ring were on the market, Tienilic acid and Suprofen, both have been withdrawn due to hepatotoxicity and cases of renal failure , this has been circumvened by introducing thiophene ring which is substituted in 4,5 positions. This may be due to sulfoxides and epoxide adducts that may interact with the GSH System and Methionine to form protein adducts.[10]

Aside from "should" being spelled wrong here, *should* this really be mentioned? I could name multiple other drugs that are still on the market which have a thiophene ring somewhere. This sentence does not appear to be covered by the incomplete citation in [10], either. Also 4,5 substitution on a 5-member ring? Start at the first atom in a five-membered ring, and count until you reach five. If you haven't yet discovered the problem here, just keep counting... (talk) 09:25, 14 April 2016 (UTC)
Yeah, that recently added paragraph has multiple problems. I have simply deleted it. -- Ed (Edgar181) 12:05, 14 April 2016 (UTC)