Talk:Emtricitabine/tenofovir

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Source requested[edit]

According to this document It seems it was developed (co-developed?) at the ? (Institute of Organic Chemistry and biochemistry) in Prague. Is there some more reliable source for this?— Preceding unsigned comment added by Jirka6 (talkcontribs) March 7, 2007


Clarification requested[edit]

"62% fewer infections in those taking Truvada and a 73% reduction in those who took a combination of Truvada and the HIV drug tenofovir."

-Truvada is combination of two drugs, emtricitabine and tenofovir. The second half of the sentence says something about taking a combination of Truvada AND "tenofovir," but tenofovir is already a component of Truvada. Are they really talking about taking Truvada and a little extra tenofovir on the side, or could this have been a mistake? — Preceding unsigned comment added by Arathur (talkcontribs) 02:18, 12 May 2012 (UTC)

Dangers[edit]

http://www.nytimes.com/2012/05/15/health/policy/taking-truvada-to-prevent-hiv-also-comes-with-risks.html

Although Truvada alone can prevent an H.I.V. infection, it cannot control one that has already taken hold. If an H.I.V.-positive patient were to take Truvada alone, or if a user were to become infected while taking it, the H.I.V. strains they carry could become drug-resistant. The infection would be hard to treat, and it could spread to other people.

To prevent drug resistance, people who want to use Truvada for prevention first would have to make sure they were H.I.V.-negative and then be retested regularly, every few months, because it is possible, though unlikely, to become infected while taking the drug. But experts testifying before the panel on Thursday acknowledged that there is no way to ensure that people taking the drug receive frequent H.I.V. tests.

Then there is the question of adherence. Skipping doses or using Truvada on occasion, as if it were a party drug, would invite both infection and the emergence of drug-resistant strains. But research shows that people are not good at sticking to the required daily regimen. In one major study, only 10 percent of the participants took Truvada as directed — Preceding unsigned comment added by 68.172.219.111 (talk) 22:26, 16 July 2012 (UTC)

What helps prevent infection?[edit]

Hey, can anyobody tell us how this pill works? What does it do in the body in order to achieve its goal ... ++--84.73.123.149 (talk) 00:21, 16 May 2014 (UTC)--++

Article talk pages are intended for discussion on how to improve the article, not discussion about the article's topic. I would recommend you look up the constituent drugs, tenofovir and emtricitabine, and see how they work. TechBear | Talk | Contributions 00:30, 16 May 2014 (UTC)

Successes, controversies & "Truvada whores"[edit]

This article should reflect the remarkable success of Truvada in HIV prophylaxis, and the fact that a certain number of gay men (denounced as "Truvada whores") are using Truvada instead of condoms. See this article in the NY Times. "Are We Ready for H.I.V.’s Sexual Revolution?" - http://www.nytimes.com/2014/05/24/opinion/sunday/ready-for-hivs-sexual-revolution.html. (If I had time, I'd add something like this to the article - but I don't have time at the moment.) Omc (talk) 23:11, 25 May 2014 (UTC)

Indeed. Similar more recent stories worth incorporating would be: this and this. These and others are linked in the pre-exposure prophylaxis article. Snori (talk) 00:31, 26 February 2017 (UTC)