Tannerella forsythia

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Scientific classification
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidetes
Order: Bacteroidales
Family: Porphyromonadaceae
Genus: Tannerella
Species: T. forsythia
Binomial name
Tannerella forsythia
Tindall 2002

Tannerella forsythia is an anaerobic, Gram-negative bacterial species of the Cytophaga-Bacteroidetes family. It has been implicated in periodontal diseases and is a member of the red complex of periodontal pathogens.[1][2] T. forsythia was previously named Bacteroides forsythus and Tannerella forsythensis.[3][4]

Tannerella forsythia was discovered by and named after Dr. Anne Tanner who works at The Forsyth Institute located in Cambridge, Massachusetts.

T. forsythia has been identified in atherosclerotic lesions. Lee et al. found that infecting mice with T. forsythia induced foam cell formation and accelerated the formation of atherosclerotic lesions.[5] It has also been isolated from women with bacterial vaginosis.[6] The presence of oral T. forsythia has been found to be associated with an increased risk of esophageal cancer.[7]

See also[edit]

List of bacterial vaginosis microbiota


  1. ^ 'Tannerella forsythensis ATCC 43037'
  2. ^ Tanner, Anne C. R.; Izard, Jacques (2006). "Tannerella forsythia, a periodontal pathogen entering the genomic era". Periodontology 2000. 42: 88–113. doi:10.1111/j.1600-0757.2006.00184.x. ISSN 0906-6713. PMID 16930308. 
  3. ^ Cionca N; et al. (2010). "Microbiologic testing and outcomes of full-mouth scaling and root planing with or without amoxicillin/metronidazole in chronic periodontitis". J Perio. 81: 15–23. doi:10.1902/jop.2009.090390. 
  4. ^ Sakamoto, Mitsuo; Suzuki, Masahito; Umeda, Makoto; Ishikawa, Isao; Benno, Yoshimi (May 2002). "Reclassification of Bacteroides forsythus (Tanner et al. 1986) as Tannerella forsythensis corrig., gen. nov., comb. nov". International Journal of Systematic and Evolutionary Microbiology. 52 (Pt 3): 841–849. doi:10.1099/00207713-52-3-841. ISSN 1466-5026. PMID 12054248. 
  5. ^ [LEE HR, JUN HK, & CHOI BK. (2014). Tannerella forsythia BspA increases the risk factors for atherosclerosis in ApoE(-/-) mice. Oral Diseases. 20, 803-8.]
  6. ^ Africa, Charlene; Nel, Janske; Stemmet, Megan (2014). "Anaerobes and Bacterial Vaginosis in Pregnancy: Virulence Factors Contributing to Vaginal Colonisation". International Journal of Environmental Research and Public Health. 11 (7): 6979–7000. doi:10.3390/ijerph110706979. ISSN 1660-4601. PMC 4113856Freely accessible. PMID 25014248. 
  7. ^ https://www.sciencedaily.com/releases/2017/12/171201090955.htm

External links[edit]

Wikidata link.PNG