Tasosartan

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Tasosartan
Tasosartan.png
Clinical data
Pregnancy
category
  • N/A
ATC code
Legal status
Legal status
  • Withdrawn
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
Chemical and physical data
Formula C23H21N7O
Molar mass 411.459 g/mol
 NYesY (what is this?)  (verify)

Tasosartan is an angiotensin II receptor antagonist.

It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug.[1][2]

References[edit]

  1. ^ Atkinson AJ, et al. (2007). Principles of clinical pharmacology. Amsterdam: Elsevier. p. 515. ISBN 0-12-369417-5. 
  2. ^ Dina R, Jafari M (July 2000). "Angiotensin II-receptor antagonists: an overview". Am J Health Syst Pharm. 57 (13): 1231–41. PMID 10902066.