Taurocholic acid

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Taurocholic acid
Taurocholic acid
Names
IUPAC name
2-{[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid
Identifiers
3D model (Jmol)
ChEBI
ChemSpider
ECHA InfoCard 100.001.216
Properties
C26H45NO7S
Molar mass 515.7058 g/mol
Melting point 125.0 °C (257.0 °F; 398.1 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Taurocholic acid, known also as cholaic acid, cholyltaurine, or acidum cholatauricum, is a deliquescent yellowish crystalline bile acid involved in the emulsification of fats. It occurs as a sodium salt in the bile of mammals. It is a conjugate of cholic acid with taurine. In medical use, it is administered as a cholagogue and choleretic.

Hydrolysis of taurocholic acid yields taurine.

For commercial use, taurocholic acid is manufactured from cattle bile, a byproduct of the meat-processing industry.[1]

This acid is also one of the many molecules in the body that has cholesterol as its precursor.

Toxicity[edit]

The median lethal dose of taurocholic acid in newborn rats is 380 mg/kg.

See also[edit]

References[edit]

  1. ^ Taurocholic acid, sodium salt at GlycoFineChem.com