The family Clusiaceae was divided by Cronquist into 2 subfamilies: the Clusioideae (typical subfamily) and the Hypericoideae. The latter was often treated as a family - the Hypericaceae or St. John's wort family. Elements of the Hypericoideae are more common in North temperate areas and those of the Clusioideae are centered in the Tropics.
Later classifications however divide the family in a finer way. The taxonomy below mostly follows that of Stevens. Molecular studies have shown that the family Podostemaceae - the riverweeds - as well as the Theaceae-segregate Bonnetiaceae need to be included in this group. Their inclusions make Clusiaceae in a wide-sense polyphyletic, and Stevens's subfamilies need to be recognised at family level: Clusioideae as Clusiaceae sensu stricto; Hypericoideae as Hypericaceae; and Kielmeyeroideae as Calophyllaceae.