Technetium (99mTc) nofetumomab merpentan

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Technetium (99mTc) nofetumomab merpentan?
Technetium-99m nofetumomab merpentan skeletal.svg
Monoclonal antibody
Type Fab fragment
Source Mouse
Clinical data
Trade names Verluma
Pharmacokinetic data
Biological half-life 10.5 hours
Excretion renal (64%)
CAS Number 165942-79-0 N
ATC code None
 N (what is this?)  (verify)

Technetium (99mTc) nofetumomab merpentan (trade name Verluma) is a mouse monoclonal antibody used in the diagnosis of lung cancer,[1] gastrointestinal, breast, ovary, pancreas, kidney, cervix, and bladder carcinoma.[2] The antibody itself, nofetumomab, is attached to the chelator merpentan, which links it to the radioisotope technetium-99m (99mTc).[3]


  1. ^ Straka, MR; Joyce, JM; Myers, DT (2000). "Tc-99m nofetumomab merpentan complements an equivocal bone scan for detecting skeletal metastatic disease from lung cancer". Clinical nuclear medicine 25 (1): 54–5. doi:10.1097/00003072-200001000-00013. PMID 10634533. 
  2. ^ Breitz, HB; Tyler, A; Bjorn, MJ; Lesley, T; Weiden, PL (1997). "Clinical experience with Tc-99m nofetumomab merpentan (Verluma) radioimmunoscintigraphy". Clinical nuclear medicine 22 (9): 615–20. doi:10.1097/00003072-199709000-00007. PMID 9298295. 
  3. ^ WHO Drug Information