Technetium (99mTc) tilmanocept

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Technetium (99mTc) tilmanocept
Technetium-99m tilmanocept.svg
Clinical data
Trade names Lymphoseek
AHFS/ lymphoseek
  • US: C (Risk not ruled out)
Routes of
Intradermal, subcutaneous
ATC code
Legal status
Legal status
Pharmacokinetic data
Elimination half-life 1.75 to 3.05 hours at injection site
Chemical and physical data
Formula (C6H10O5)n(C19H28N4O9S99mTc)3–8(C13H24N2O5S2)12–20(C5H11NS)0–17
Molar mass 15,281–23,454 g/mol[1]

Technetium (99mTc) tilmanocept, trade name Lymphoseek, is a radiopharmaceutical diagnostic imaging agent approved by the U.S. Food and Drug Administration (FDA) for the imaging of lymph nodes.[1][2] It is used to locate those lymph nodes which may be draining from tumors, and assist doctors in locating those lymph nodes for removal during surgery.[3]


  1. ^ a b FDA Professional Drug Information
  2. ^
  3. ^ Marcinow, A. M.; Hall, N.; Byrum, E.; Teknos, T. N.; Old, M. O.; Agrawal, A. (2013). "Use of a novel receptor-targeted (CD206) radiotracer, 99mTc-tilmanocept, and SPECT/CT for sentinel lymph node detection in oral cavity squamous cell carcinoma: Initial institutional report in an ongoing phase 3 study". JAMA Otolaryngology–Head & Neck Surgery. 139 (9): 895–902. doi:10.1001/jamaoto.2013.4239. PMC 4301415. PMID 24051744.