Telmisartan/hydrochlorothiazide

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Telmisartan/hydrochlorothiazide
Combination of
TelmisartanAngiotensin II receptor antagonist
HydrochlorothiazideThiazide diuretic
Clinical data
Trade namesMicardisPlus, Micardis HCT, others
MedlinePlusa611031
License data
Pregnancy
category
  • AU: D
  • US: D (Evidence of risk)
Routes of
administration
By mouth
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
PubChem CID
KEGG
CompTox Dashboard (EPA)
  (verify)

Telmisartan/hydrochlorothiazide, sold under the names Micardis HCT among others, is a medication used to treat high blood pressure.[1] It is a combination of telmisartan an angiotensin II receptor antagonist with hydrochlorothiazide a diuretic.[1] It may be used if telmisartan by itself is not sufficient.[2] It is taken by mouth.[2]

Common side effects include dizziness, upper respiratory tract infections, nausea, diarrhea, and tiredness.[1] Severe side effects may include kidney problems, electrolyte problems, and allergic reactions.[1] Use during pregnancy may harm the baby.[1] Telmisartan works by blocking the effects of angiotensin II while hydrochlorothiazide works by decreasing the kidneys' ability to retain water.[1]

The combination was approved for medical use in the United States in 2000.[3] The combination is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[4] It is available as a generic medication.[2] A month of medication costs the NHS about £17 as of 2018.[2] In the United States it costs about US$65 per month as of 2019.[5]

References[edit]

  1. ^ a b c d e f "DailyMed - TELMISARTAN AND HYDROCHLOROTHIAZIDE tablet". dailymed.nlm.nih.gov. Retrieved 29 October 2019.
  2. ^ a b c d British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 178. ISBN 9780857113382.
  3. ^ "Hydrochlorothiazide and telmisartan Uses, Side Effects & Warnings". Drugs.com. Retrieved 29 October 2019.
  4. ^ "World Health Organization model list of essential medicines: 21st list 2019". 2019. hdl:10665/325771. Cite journal requires |journal= (help)
  5. ^ "Hydrochlorothiazide/telmisartan Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 29 October 2019.

External links[edit]