Template:SerotypeA normal

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HLA-A{{{type}}}
(MHC Class I, A cell surface antigen)
Illustration HLA-A.png
HLA-A{{{type}}}
About
Protein transmembrane receptor/ligand
Structure αβ heterodimer
Subunits HLA-A*{{{allelegroup}}}--, β2-microglobulin
Subtypes
Subtype
allele
Available structures
A0 *0000
{{{cNick2}}} *{{{allelegroup}}}{{{cAllele2}}}
{{{cNick3}}} *{{{allelegroup}}}{{{cAllele3}}}
{{{cNick4}}} *{{{allelegroup}}}{{{cAllele4}}}
Alleles link-out to IMGT/HLA database at EBI

HLA-A{{{type}}} (A{{{type}}}) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α{{{type}}} subset of HLA-A α-chains. For A{{{type}}}, the alpha "A" chain are encoded by the HLA-A*{{{allelegroup}}} allele group and the β-chain are encoded by B2M locus.[1] A{{{type}}} and A*{{{allelegroup}}} are almost synonymous in meaning.


Serotype[edit]

A0 recognition of some HLA A*00 gene products[2]
A*00 A0 Sample
allele  % size (N)
*0000 0 0


References

  1. ^ Arce-Gomez B, Jones EA, Barnstable CJ, Solomon E, Bodmer WF (February 1978). "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin". Tissue Antigens. 11 (2): 96–112. PMID 77067. doi:10.1111/j.1399-0039.1978.tb01233.x. 
  2. ^ Allele Query Form IMGT/HLA - European Bioinformatics Institute