Tenascin-R

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TNR
Protein TNR PDB 1tdq.png
Identifiers
Aliases TNR, TN-R, tenascin R
External IDs MGI: 99516 HomoloGene: 124416 GeneCards: TNR
RNA expression pattern
PBB GE TNR 206990 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003285
NM_001328635

NM_022312

RefSeq (protein)

NP_001315564
NP_003276
NP_003276.3

NP_071707.2
NP_071707

Location (UCSC) Chr 1: 175.32 – 175.74 Mb Chr 1: 159.52 – 159.93 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Tenascin-R is a protein that in humans is encoded by the TNR gene.[3][4][5]

Function[edit]

Tenascin-R (TNR) is an extracellular matrix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion), TNX (TNXB), and TNR.[6] The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues.[supplied by OMIM][5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Carnemolla B, Leprini A, Borsi L, Querzé G, Urbini S, Zardi L (April 1996). "Human tenascin-R. Complete primary structure, pre-mRNA alternative splicing and gene localization on chromosome 1q23-q24". The Journal of Biological Chemistry. 271 (14): 8157–60. doi:10.1074/jbc.271.14.8157. PMID 8626505. 
  4. ^ Leprini A, Gherzi R, Siri A, Querzé G, Viti F, Zardi L (December 1996). "The human tenascin-R gene". The Journal of Biological Chemistry. 271 (49): 31251–4. doi:10.1074/jbc.271.49.31251. PMID 8940128. 
  5. ^ a b "Entrez Gene: TNR tenascin R (restrictin, janusin)". 
  6. ^ Erickson HP (October 1993). "Tenascin-C, tenascin-R and tenascin-X: a family of talented proteins in search of functions". Current Opinion in Cell Biology. 5 (5): 869–76. doi:10.1016/0955-0674(93)90037-Q. PMID 7694605. 

Further reading[edit]