Terizidone

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Terizidone
Terizidone.svg
Systematic (IUPAC) name
4,4'-{1,4-Phenylenebis[(E)methylylidene
(E)azanylylidene]}bis(1,2-oxazolidin-3-one)
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy
category
  • C
Identifiers
CAS Number 25683-71-0 N
ATC code J04AK03 (WHO)
PubChem CID 65720
ChemSpider 59144 YesY
UNII 1199LEX5N8 YesY
KEGG D07247 YesY
Synonyms 4-[({4-[N-(3-oxo-1,2-oxazolidin-4-yl)carboximidoyl]phenyl}methylidene)amino]-1,2-oxazolidin-3-one
Chemical data
Formula C14H14N4O4
Molar mass 302.286 g/mol
 NYesY (what is this?)  (verify)

Terizidone is a drug used in the treatment of tuberculosis.[1] Terizidone is used mainly used in multi-drug-resistant tuberculosis (MDR-TB) in conjunction with other second-line drugs. It is a derivate of cycloserine and it is bacteriostatic.[2]

References[edit]

  1. ^ "[Tolerability to terizidone (TZ) in the treatment of pulmonary tuberculosis in dialyzed patients]". Minerva Med. 82 (7-8): 477–81. 1991. PMID 1922892. 
  2. ^ Rossiter, Dawn (2012). South African Medicines Formulary. Cape Town, South Africa: Health and Medical Publishing Group of the South African Medical Association. pp. 323–325. ISBN 978-1-875098-28-6.