Texaphyrin is a sub-class of heterocyclic macrocycle molecules known as porphyrins. The molecule was invented by University of Texas at Austin professor Jonathan Sessler. The name texaphryin arose because some of the molecules have a shape that can superimpose onto the points of the star featured on the state flag of Texas. Texaphyrins were nominated as the "State Molecule of Texas", but the buckyball was chosen instead.
Sessler has described possible medicinal uses of these compounds in the Proceedings of the National Academy of Sciences and other scientific journals. Pharmacyclics, Inc., a publicly traded company begun by Sessler, licensed the technology behind texaphyrins from the university to develop commercial and medical uses for the molecules. One is being developed under the name Antrin. Two predicted applications will be in neoplastic and cardiovascular disease.
- Dr. Sessler's Lab home page at the University of Texas
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