The venue consists of two auditoriums and one outdoor stage and is used for various live performances all year round. The Main Hall is a 2,000-seat auditorium, and is used for stage presentations, concerts and conferences. The Small Hall is a 500-seat multi-purpose auditorium, which is integrated with a 1,000-seat outdoor amphitheater. The Social Education and Exhibition Building accommodates a cultural library and the Thai Life Permanent Exhibition. There is also the Japanese Pavilion and the Thai Pavilion.
The Bangkok Metro has a station called Thailand Cultural Centre. As the crow flies the station is near to the centre, but to get there one has to walk around a huge enclosed parking lot, a 10-minute walk. Out of the station's exit 1, turn right and again at the next major intersection. Signage at the station is not good, but is at the first intersection.
The station has been designed to be an interchange providing future connection with the Orange Line. The Orange Line is planned to run from Bang Kapi to Bang Bamru and cut perpendicularly with the Blue Line at Thailand Cultural Centre station.