Musical genres played there included techno and house on Saturday nights; drum and bass and breakbeat on Friday night; as well as indie on Monday nights. The End also hosted other nights throughout the week and weekend, including a dubstep night on Wednesdays.
Since its opening in 1995, many DJs played at significant points in their careers. Stewart Essence (ElusiveWax), groundbreaking with his marathon deep house sets. Roni Size won the Mercury Music Prize whilst hosting a residency at the club in 1997. Fatboy Slim was resident at the club when he went to number one in the UK charts in 1998, Layo & Bushwacka! released album Lowlife in 1999, Zero 7 were residents at the club for two years in the run-up to the 2001 release of Simple Things, Scissor Sisters played their first UK gig at the club, and Erol Alkan went from being chosen as Best Breakthrough DJ at the 2002 Muzik Awards through to winning Mixmag’s DJ of the year in 2006.
Due to slump in the property market, the property developers decided against turning The End into a block of flats, instead joining forces with some club promoters (John Alist) to open the venue up again in May 2009 as The Den.