The Medicine Bar in Birmingham, England started as a collaboration in the 1990s between the London Medicine bar and local hip hop DJ 'Simon Fat Head', who began his career at the legendary 'Brothers and Sisters' at the 'Coast to Coast' club on Broad Street.
Substance (which evolved out of Amplified) is the longest running hip hop night in the bar, with DJs Roc1, Magoo, Chris Reid (also from Scratch in London) and MC Mad Flow. It has brought hip hop acts including Afrika Bambaata, De La Soul and Jeru the Damaja to Birmingham.
Leftfoot is the bar's main funk and soul night which is part run by ex Rockers Hi-Fi DJ Dick and Adam Regan (who now owns the Bull's Head bar in the birmingham suburb of Moseley). Leftfoot hosts many large acid Jazz type events with appearances from Gilles Peterson to Mr Scruff. Both nights feature live acts.
For a short period in 2006/07, the Medicine Bar hosted the Birmingham leg of Club NME.