The Perfect Prescription is the second studio album by Spacemen 3. It is a concept album, "a vision of a drug trip from inception to its blasted conclusion, highs and lows fully intact." The music becomes progressively more orchestral and serene until the high of the trip, represented by "Ecstasy Symphony"/"Transparent Radiation (Flashback)," moving on to the moment of realisation where the high has faded and the comedown ensues, represented by the harsh opening guitar chords in "Things'll Never Be the Same." Coming down is represented in the blues based "Come Down Easy," whilst the potentially fatal effects of an overdose are portrayed in the final track "Call the Doctor." The music was written by the band except "Transparent Radiation" which is a Red Krayola cover from their 1967 album Parable of Arable Land. The band also borrow heavily from the gospel standard "In My Time of Dying," for "Come Down Easy" and pay homage to Lou Reed in "Ode to Street Hassle."
The vinyl edition of The Perfect Prescription includes liner notes by author R. Hunter Gibson:
"'The Perfect Prescription' is an album that will be left out of the rock 'n' roll readers, just as the great texts bid Bo Diddley throw down his cloak for the quickstep of Eddie Cochran.
If there has ever been an untrumpeted classic, here it is. An arcane, apocryphal document, this record, in late '80s UK, was telegraphing a message of unconcerned hope in a world hypnotised by guilt-ridden social work rock. Here, more than anywhere, Spacemen 3 have a vested interest in absolutely nothing.
It is revolutionary and militant where most angry young rock is liberal at best. It is extreme and accurate. Like 'Aftermath' it captures every aspect of the age that would later be analysed. As the unassuming soundtrack of a country breaking down and a world breaking up, its very nature means that it has been ignored.
Spacemen 3, like all the great rock 'n' rollers, from Arthur Parker to Paul Gauguin, are revolutionary; this is their great manifesto, striding free from the pharmacy raid of their debut armed with the keys of the musical medicine cabinet. When we left off things would never be the same. But the other side of the locked door, well, it's like the white one in the story.
If 'Sound of Confusion' denied the wider stretches of the sense in favour of the immediately, roughly sensual, this script panned out from some suburban global village Viet vet subculture into a poppyfield undersown with righteous paranoia. And still the smell of burning rubber on trash yankee wheels thickens the air...