There have been 42 episodes since the documentary first aired on 3 April 2012, split into nine separate series and a few additional episodes. The documentary has been narrated by Sally Phillips throughout. Brent Zillwood had a big impact on the programme over the first two seasons as he helped raise awareness for Tourette's syndrome internationally.
Stand-up comedian Luke has Tourette's. He is reluctant to approach a girl in case he calls her a slag - or worse. How will he cope when he meets Lucy, who has never known anyone with Tourette's before?
Justin & Shaine
Justin has tumors on his body and face, and has never been out with a girl. He goes on a date with Tracey. Shaine has a learning disability. He can write a lady a poem but struggles to ask women out.
Hadyn & Sam
Hadyn has undergone 40 facial operations and is partially deaf. His twin brother hopes to help Haydn get over his lack of confidence with girls and find a girlfriend.
Michael's autism makes conversation difficult; Brent from Plymouth has Tourette's syndrome; and Sarah from Hertfordshire has expressive aphasia, which makes communication hard.
Sam, Ray & Steve
Featuring Sam, 34, who has achondroplasia, the most common type of dwarfism, Ray is 49, an office-worker who has a learning disability, and Steve, 30, who has a facial disfigurement, Crouzon Syndrome.
Kate, Damian & Oliver
The Undateables this time include incurable romantic Kate, who has Down's Syndrome, and Damian, who has albinism and whose dream date is a moonlit picnic in the park.
Heather, Gareth & Matthew
Heather has severe OCD. Gareth has brittle bones and has broken his legs over 150 times. Matthew has autism. Can the three of them find partners?
How does James fare on a first date with Chloe? Will Tammy get over her first date nerves? And as Tom prepares to meet with Megan, what will he reveal of his Tourette's and Asperger's?
James, Lucas & Tom
James has a learning disability and has not had a girlfriend in 10 years. Lucas has facial dysplasia and wants to conquer his fear of being rejected. And Tom is looking for love of the magical kind.
George, David & Bethany
George, who is paralysed from the chest down, meets Nathalie; magician David, who has a learning disability, goes on a first date with Claire; and Bethany, who has Downs syndrome, meets Bradley.
Some of the Undateables from previous shows embark on romantic adventures overseas, including Alex and Eloise in France, and Brent and Challis in Amsterdam.
Steve, who has Crouzon Syndrome, prepares to marry Vicky, while Matthew is concerned that his stammer may hinder his bid to propose to Jessica.
Jason is a transport buff with autism. Vlogger Charley has cerebral palsy. And Souleyman is a sprinter going blind, whose search for love is a race against the clock.
Kaia, Rhys & Joshua
Cooking enthusiast Kaia is profoundly deaf. James Bond fanatic Rhys is autistic. Keen gardener Joshua is also autistic. Can these three young people find a partner?
Sam, Katy & Donovan
Movie fan Sam, who is autistic, looks for his leading lady. Katy, who has Tourette's, seeks a man who accepts her for who she is. And Donovan is looking to bag a second date.
Richard, Lizzie, Eddie & Sam
Richard is 43 and autistic and last year managed his first ever second date. Can he now build on this success with Anna? There's also postman Sam. And the show also catches up with Lizzie and Eddie.
Shaine, Lily, Ray & George
Poet Shaine and Gemma celebrate their first anniversary, as ghost hunter Lily and charity worker Ray go looking for love again.
More singles looking for love. Like rugby player Luke, who has Tourette's, and Sam, who has Asperger's and finds the gay scene intimidating. There is also self-confessed romantic Becky.
Nisar, Daniel & Fatima
Trainee accountant and Bollywood fan Nisar has a stammer, grunge-lover Daniel has Asperger's and fashionista Fatmina has dwarfism.
Amber, Richard & Nick
The love-seekers this time include Amber, who suffered a major stroke eight years ago. Having learned to walk and talk again, Amber's ready to find her Prince Charming. There's also Nick and Richard.
Alex, Jason & Tom
The singletons looking for love are airplane buff Jason, rugby player and model Tom, and Alex - proud owner of a new sports car.
Daniel, Shaine, Ray & Sam
Rock star Daniel is dreaming of a girlfriend for Christmas. Poet Shaine is getting in the mistletoe. Ray plans a romantic date. And postman Sam plans to ask Francesca if she will be his girlfriend.
There was a lot of controversy surrounding this show when it was first introduced from newspaper companies such as The Mirror and The Guardian, due to the word 'undateable' being used in the title to describe people with mental and physical disabilities. However, Channel 4 claim the title of the series was based upon Society's preconceptions. The Undateables faced a lot of back lash from Doctors who branded the show "offensive" and "exploitative". Dr Rachael Pickering said the series left her "disturbed at being part of a society that might seek to view disabled people as a source of comedy". She also spoke with the BMA, British Medical Association, annual representatives about the danger of patients being exploited by the TV documentary.  In an interview with Holly Willoughby and Phillip Schofield on This Morning one of the stars of the show, Tammy, has said she finds it insulting that she would be exploited in any way, as she goes on to say that she is disfigured, not stupid.