After the release and success of his critically acclaimed debut studio albumShock of the Hour in late 1993, MC Ren immediately began working on his sophomore album. The deaths of DJ Train and Eazy-E would however prove to be a huge setback and Ren stepped of the scene for a while. Meanwhile, he continued his work with the Nation of Islam, and visited Egypt in mid-1995. Following his return from Egypt, MC Ren continued to work on his album, this time however scrapping all the material he recorded with DJ Train. Enlisting Cold 187um and Dr. Jam to produce his album, Ren began recording new material that didn't deviate from clichéd G-funk grooves.
While making The Villain in Black, MC Ren was closely affiliated with the Nation of Islam, which had a large impact on the some parts of the album's content. Khalid Muhammad appeared in the track "Muhammad Speaks," where he spoke about the history of the rights of African-Americans. He also made an appearance on the closing track "Bring It On".