Thiobutabarbital

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Thiobutabarbital
(RS)-Thiobutabarbital Structural Formula V1.svg
Clinical data
SynonymsThiobutabarbital, Inactin, Brevinarcon, 5-sec-Butyl-5-ethyl-2-thiobarbituric acid
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ECHA InfoCard100.016.600 Edit this at Wikidata
Chemical and physical data
FormulaC10H16N2O2S
Molar mass228.312 g/mol g·mol−1
3D model (JSmol)
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Thiobutabarbital (Inactin, Brevinarcon) is a short-acting barbiturate derivative invented in the 1950s. It has sedative, anticonvulsant and hypnotic effects, and is still used in veterinary medicine for induction in surgical anaesthesia [1]

Stereochemistry[edit]

Thiobutabarbital contains a stereocenter and consists of two enantiomers. This is a racemate, ie a 1: 1 mixture of ( R ) - and the ( S ) - form:[2]

Enantiomers of Thiobutabarbital
(R)-Thiobutabarbital Structural Formula V1.svg
(R)-Form
(S)-Thiobutabarbital Structural Formula V1.svg
(S)-Form

References[edit]

  1. ^ Rieg T, Richter K, Osswald H, Vallon V. Kidney function in mice: thiobutabarbital versus alpha-chloralose anesthesia. Naunyn Schmiedebergs Archives of Pharmacology. 2004 Oct;370(4):320-3.
  2. ^ Entry on Thiobutabarbital. at: Römpp Online. Georg Thieme Verlag, retrieved 15. Juni 2014.