Thioinosinic acid

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Thioinosinic acid
Thioinosinic acid.png
Ball-and-stick model of the thioinosine monophosphate anion
Names
IUPAC name
[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-sulfanylidene-3H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate
Other names
Thioinosine monophosphate (TIMP)
Identifiers
3D model (Jmol)
ChemSpider
ECHA InfoCard 100.000.168
Properties
C10H13N4O7PS
Molar mass 364.27 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Thioinosinic acid (or thioinosine monophosphate, TIMP) is an intermediate metabolite of azathioprine, an immunosuppressive drug.[1][2]

References[edit]

  1. ^ Steinhilber, D; Schubert-Zsilavecz, M; Roth, HJ (2005). Medizinische Chemie (in German). Stuttgart: Deutscher Apotheker Verlag. p. 340. ISBN 3-7692-3483-9. 
  2. ^ Sahasranaman, S.; Howard, D.; Roy, S. (2008). "Clinical pharmacology and pharmacogenetics of thiopurines". European Journal of Clinical Pharmacology. 64 (8): 753–767. doi:10.1007/s00228-008-0478-6. PMID 18506437.