Thiosulfate sulfurtransferase

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thiosulfate sulfurtransferase
Identifiers
EC number 2.8.1.1
CAS number 9026-04-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a thiosulfate sulfurtransferase (EC 2.8.1.1) is an enzyme that catalyzes the chemical reaction

thiosulfate + cyanide sulfite + thiocyanate

Thus, the two substrates of this enzyme are thiosulfate and cyanide, whereas its two products are sulfite and thiocyanate.

This enzyme belongs to the family of transferases, specifically the sulfurtransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is thiosulfate:cyanide sulfurtransferase. Other names in common use include thiosulfate cyanide transsulfurase, thiosulfate thiotransferase, rhodanese, and rhodanase.

Structural studies[edit]

As of late 2007, 11 structures have been solved for this class of enzymes, with PDB accession codes 1BOH, 1BOI, 1DP2, 1E0C, 1H4K, 1H4M, 1ORB, 1RHD, 1RHS, 1UAR, and 2ORA.

References[edit]

  • Sorbo BH; Lagerkvist, Ulf; Pesola, Rainer; Virtanen, Artturi I.; Sörensen, Nils Andreas (1953). "Crystalline rhodanese. I. Purification and physicochemical examination". Acta Chem. Scand. 7: 1129–1136. doi:10.3891/acta.chem.scand.07-1129. 
  • Sorbo BH; Lagerkvist, Ulf; Pesola, Rainer; Virtanen, Artturi I.; Sörensen, Nils Andreas (1953). "Crystalline rhodanese. II. The enzyme catalyzed reaction". Acta Chem. Scand. 7: 1137–1145. doi:10.3891/acta.chem.scand.07-1137. 
  • Westley J; Green JR (1959). "Crystalline beef kidney rhodanese". J. Biol. Chem. 234: 2325–6. PMID 13844173. 
  • Thiosulfate Sulfurtransferase at the US National Library of Medicine Medical Subject Headings (MeSH)