Thiothixene

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Thiothixene
Thiothixene.svg
Systematic (IUPAC) name
(9Z)-N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
Clinical data
Trade names Navane
AHFS/Drugs.com monograph
MedlinePlus a682867
Legal status
  • (Prescription only)
Routes of
administration
Oral
Pharmacokinetic data
Metabolism Hepatic
Biological half-life 10-20 hours
Identifiers
CAS Registry Number 5591-45-7 YesY
ATC code N05AF04
PubChem CID: 941651
IUPHAR/BPS 212
DrugBank DB01623 YesY
ChemSpider 819430 YesY
UNII 7318FJ13YJ YesY
ChEMBL CHEMBL1201 YesY
Chemical data
Formula C23H29N3O2S2
Molecular mass 443.627 g/mol
 YesY (what is this?)  (verify)

Tiotixene (INN) or Thiothixene (USAN; Navane) is a typical antipsychotic drug of the thioxanthene class used in the treatment of psychoses like schizophrenia. It was introduced on July 24, 1967[1] by Pfizer.[2]

See also[edit]

References[edit]

  1. ^ http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm
  2. ^ José Miguel Vela; Helmut Buschmann; Jörg Holenz; Antonio Párraga; Antoni Torrens (2007). Antidepressants, Antipsychotics, Anxiolytics: From Chemistry and Pharmacology to Clinical Application. Weinheim: Wiley-VCH. p. 520. ISBN 3-527-31058-4.