Thujaplicins (isopropyl cycloheptatrienolones) are series of related chemical substances discovered in the 1930s and isolated from Thuja plicata (western redcedar tree). The three compounds are α-thujaplicin, β-thujaplicin (hinokitiol), and γ-thujaplicin. They are known for potent anti-fungal and anti-bacterial properties. They are also known to be potent antioxidants. They were the first natural tropolones to be made synthetically, by Ralph Raphael and colleagues.
- Erdtman, H.; Gripenberg, J. (1948). "Antibiotic substances from the heart wood of Thuja plicata Don". Nature. 161 (4097): 719. doi:10.1038/161719a0.
- Chedgy, R. J.; Lim, Y. W.; Breuil, C. (2009). "Effects of leaching on fungal growth and decay of Western red cedar (Thuja plicata)". Canadian Journal of Microbiology. 55 (5): 578–586. doi:10.1139/W08-161. PMID 19483786.
- Chedgy, R. (2010). Secondary Metabolites of Western Red Cedar (Thuja plicata). Lambert Academic Publishing. ISBN 978-3-8383-4661-8.
- Cook, J.W.; Scott, A.I.; Raphael, R.A. (1951). "Tropolones. Part II. The synthesis of α-, β-, and γ-thujaplicins". J. Chem. Soc.: 695–698. doi:10.1039/JR9510000695.
|This article about a ketone is a stub. You can help Wikipedia by expanding it.|