Thymidine triphosphate

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Thymidine triphosphate
Skeletal formula of thymidine triphosphate, 3- negative charge
Space-filling model of the thymidine triphosphate molecule, 4- negative charge
IUPAC name
[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
Other names
dTTP, 2'-deoxythymidine triphosphate
365-08-2 N=
ChemSpider 58493 N=
Jmol 3D model Interactive image
MeSH thymidine+5'-triphosphate
PubChem 64968
Molar mass 482.168
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is YesYN ?)
Infobox references

Deoxythymidine triphosphate (dTTP) is one of the four nucleotide triphosphates that are used in the in vivo synthesis of DNA. Unlike the other deoxyribonucleotide triphosphates, thymidine triphosphate does not always contain the "deoxy" prefix in its name.[1] The corresponding ribonucleoside triphosphate is called uridine triphosphate.

It can be used by DNA ligase to create overlapping "sticky ends" so that protruding ends of opened microbial plasmids may be closed up.


  1. ^ Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.