Thymidylate 5'-phosphatase
| thymidylate 5′-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.3.35 | ||||||||
| CAS no. | 9026-80-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme thymidylate 5′-phosphatase (EC 3.1.3.35) catalyzes the reaction
- thymidylate + H2O thymidine + phosphate
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is thymidylate 5′-phosphohydrolase. Other names in common use include thymidylate 5′-nucleotidase, deoxythymidylate 5′-nucleotidase, thymidylate nucleotidase, deoxythymidylic 5′-nucleotidase, deoxythymidylate phosphohydrolase, and dTMPase.
References[edit]
- Aposhian HV, Tremblay GY (1966). "Deoxythymidylate 5′-nucleotidase. Purification and properties of an enzyme found after infection of Bacillus subtilis with phage SP5C". J. Biol. Chem. 241 (21): 5095–101. PMID 4958986.
