Tiazofurin

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Tiazofurin
Tiazofurin.svg
Clinical data
ATC code L01XX18 (WHO)
Identifiers
Synonyms 2-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide
CAS Number 60084-10-8 N
PubChem (CID) 457954
ChemSpider 403014 YesY
UNII ULJ82834RE YesY
ChEMBL CHEMBL108358 YesY
Chemical and physical data
Formula C9H12N2O5S
Molar mass 260.268 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Tiazofurin is an inhibitor of IMP dehydrogenase. Tiazofurin and its analogues are under investigation for potential use in the treatment of cancer.[1]

References[edit]

  1. ^ Popsavin M, Torović L, Svircev M, et al. (2006). "Synthesis and antiproliferative activity of two new tiazofurin analogues with 2'-amido functionalities". Bioorg. Med. Chem. Lett. 16 (10): 2773–6. doi:10.1016/j.bmcl.2006.02.001. PMID 16495053.