Tiodazosin

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Tiodazosin
Tiodazosin.svg
Names
IUPAC name
[4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(5-methylsulfanyl-1,3,4-oxadiazol-2-yl)methanone
Identifiers
3D model (Jmol)
ChemSpider
Properties
C18H21N7O4S
Molar mass 431.47 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tiodazosin is an alpha-1 adrenergic antagonist.[1]

Synthesis[edit]

Tiodazosin synthesis:[2]

See also[edit]

References[edit]

  1. ^ Chiang, J; Hermodsson, G; Oie, S (1991). "The effect of alpha 1-acid glycoprotein on the pharmacological activity of alpha 1-adrenergic antagonists in rabbit aortic strips". The Journal of pharmacy and pharmacology. 43 (8): 540–7. doi:10.1111/j.2042-7158.1991.tb03533.x. PMID 1681068. 
  2. ^ R. A. Partyka and R. R. Crenshaw, U.S. Patent 4,001,237 (1977); Chem. Abstr., 86; 140028r (1977).