Transfluthrin

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Transfluthrin
Transfluthrin-2D-skeletal.png
Names
Preferred IUPAC name
(2,3,5,6-Tetrafluorophenyl)methyl (1R,3S)-3-(2,2-dichloroethen-1-yl)-2,2-dimethylcyclopropane-1-carboxylate
Other names
– CA: (1R-trans)-(2,3,5,6-tetrafluorophenyl)methyl 3-(2,2-dichloroethenyl)-2,2- dimethylcyclopropanecarboxylate[1]
– Common name transfluthrin: E-ISO (published).
– Synonym: benfluthrin (Bayer), NAK 4455[1]
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.100.666 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C15H12Cl2F4O2/c1-15(2)7(3-10(16)17)11(15)14(22)23-5-6-12(20)8(18)4-9(19)13(6)21/h3-4,7,11H,5H2,1-2H3/t7-,11+/m1/s1 checkY
    Key: DDVNRFNDOPPVQJ-HQJQHLMTSA-N checkY
  • InChI=1/C15H12Cl2F4O2/c1-15(2)7(3-10(16)17)11(15)14(22)23-5-6-12(20)8(18)4-9(19)13(6)21/h3-4,7,11H,5H2,1-2H3/t7-,11+/m1/s1
    Key: DDVNRFNDOPPVQJ-HQJQHLMTBF
  • Cl/C(Cl)=C/[C@@H]2[C@@H](C(=O)OCc1c(F)c(F)cc(F)c1F)C2(C)C
Properties
C15H12Cl2F4O2
Molar mass 371.15 g·mol−1
Appearance Colorless crystals
Density 1.507 g/cm3 (23 °C)
Melting point 32 °C (90 °F; 305 K)
Boiling point 135 °C (275 °F; 408 K) at 0.1 mm Hg
~ 250 °C at 760 mm Hg
5.7×10−5 g/L = 57 µg/L
Solubility in hexane, isopropanol, toluene, dichloromethane very soluble
Vapor pressure 10−4 Pa (20 °C; 15 μg/m3)[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Transfluthrin is a fast-acting pyrethroid insecticide with low persistency. It has the molecular formula C15H12Cl2F4O2.

Transfluthrin can be used in the indoor environment against flies, mosquitoes, moths and cockroaches. It is a relatively volatile substance and acts as a contact and inhalation agent.[1]

Transfluthrin, if used contrary to product instructions, may cause symptoms of poisoning including nervousness, anxiety, tremor, convulsions, skin allergies, sneezing, running nose and irritation.[3] No specific antidotes are known, but symptomatic treatment with antihistamines may help to control any allergies.[3]

In experiments, transfluthrin was shown to kill 85 percent of mosquitos within one hour of exposure at concentrations below 0.3 µg/m3 (which was the detection limit) in air.[4] (The data suggests that transfluthrin is effective at these concentrations within much less than an hour of exposure.)

Various household transfluthrin products such as vaporizers and mosquito coils may result in concentrations of 15 µg/m3 to 40 µg/m3.[5] In the EU, the acceptable exposure level (AEL) for humans is 500 µg/m3.[5]

See also[edit]

References[edit]

  1. ^ a b c "WHO Specifications and evaluations for public health pesticides: Transfluthrin. WHO specification 741/2006 – Evaluation Report 741/2002 (November 2006)" (PDF). World Health Organization (WHO). November 2006. p. 20. Retrieved 15 May 2020.
  2. ^ Pesticides properties database. K Lewis et al., DOI: 10.1080/10807039.2015.1133242
  3. ^ a b Information on the leaflet supplied with the product: Good Knight Advanced (ACTIV+ System) Mosquito Repellent Vaporizer cartridge (UPC Code:8 901157 001143)
  4. ^ N.J. Martin et al., The impact of transfluthrin on the spatial repellency of the primary malaria mosquito vectors in Vietnam: Anopheles dirus and Anopheles minimus.. Malar J 19, 9 (2020)
  5. ^ a b Assessment report: Transfluthrin for EU regulation No. 528/2012 (2014)

External links[edit]