Translocated actin-recruiting phosphoprotein

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Translocated actin-recruiting phosphoprotein
Symbol tarp
UniProt O84462

The translocated actin-recruiting phosphoprotein (Tarp) is a protein that may mediate the invasion of epithelial cells by Chlamydia trachomatis using a type three secretion system.[1][2][3][4][5]


  1. ^ Wang J, Chen L, Chen F, Zhang X, Zhang Y, Baseman J, Perdue S, Yeh IT, Shain R, Holland M, Bailey R, Mabey D, Yu P, Zhong G (2009), "A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice", Vaccine, 27 (22): 2967–2980, PMC 2680781Freely accessible, PMID 19428908, doi:10.1016/j.vaccine.2009.02.095 
  2. ^ Clifton DR, Dooley CA, Grieshaber SS, Carabeo RA, Fields KA, Hackstadt T (2005), "Tyrosine phosphorylation of the Chlamydial effector protein Tarp is species specific and not required for recruitment of actin", Infection and Immunity, 73 (7): 3860–3868, PMC 1168552Freely accessible, PMID 15972471, doi:10.1128/IAI.73.7.3860-3868.2005 
  3. ^ Clifton DR, Fields KA, Grieshaber SS, Dooley CA, Fischer ER, Mead DJ, Carabeo RA, Hackstadt T (2004), "A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin", Proceedings of the National Academy of Sciences of the USA, 101 (27): 10166–10171, PMC 454183Freely accessible, PMID 15199184, doi:10.1073/pnas.0402829101 
  4. ^ Engel J (2004), "Tarp and Arp: How Chlamydia induces its own entry", Proceedings of the National Academy of Sciences of the USA, 101 (27): 9947–9948, PMC 454194Freely accessible, PMID 15226494, doi:10.1073/pnas.0403633101 
  5. ^