Trauma Center: Under the Knife 2

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Trauma Center: Under the Knife 2
Trauma Center - Under the Knife 2 Coverart.png
Developer(s) Atlus
Publisher(s) Atlus
Director(s) Daisuke Kanada
Composer(s) Manabu Namiki
Noriyuki Kamikura
Series Trauma Center
Engine Vanguard Trauma Center Engine
Platform(s) Nintendo DS
Genre(s) Simulation, Visual novel
Mode(s) Single-player

Trauma Center: Under the Knife 2[a] is a simulation game developed for the Nintendo DS and the third in the Trauma Center series. The game is a sequel to Trauma Center: Under the Knife. The character designs of Under the Knife 2 were provided by Masayuki Doi, who worked on Trauma Center: Second Opinion, instead of Maguro Ikehata, who worked on the original Under the Knife.


The player conducts the operation on the touch screen, while the top screen displays the score, time limit, and information from the nurse.

The gameplay of Trauma Center: Under the Knife 2 is similar to its predecessor, featuring improved graphics and surgical instruments. The game is divided into multiple chapters on a linear plotline. In each chapter, the player must complete an operation using the Touch Screen. The player is ranked based on multiple scoring factors. Once a chapter is completed, it can be replayed on another difficulty level. Extra, difficult chapters are unlocked upon the game's completion. Surgical tools used include the surgical laser, antibiotic gel, drain, forceps, ultrasound, magnification tool, scalpel, needle, syringe, defibrillator, wire, and an air compressor and penlight in extenuating circumstances. The player can also use the Healing Touch once per operation to slow time.


The game is set in 2021, three years after its predecessor where Dr. Derek Stiles, the protagonist, and his nurse, Angie Thompson, travel to the war-ravaged African nation of Costigar to help out at one of their hospitals. While there, they begin to research a new disease, which becomes serious enough for Derek to use the Healing Touch on a patient, the first time in years. Soon after this, Derek and Angie are called back to the Caduceus headquarters, Derek’s medical organization, to investigate a new GUILT-related disease tentatively called Post-GUILT Syndrome, a series of critical conditions that affect any patients with past GUILT exposure.

Elsewhere, the medical terrorist organization Delphi returns and begins causing outbreaks of GUILT. The police raid some of their hideouts, but are unable to find their headquarters until they kidnap Derek and Angie. After they escape, the police and a new medical organization called the Hands of Asclepius (HOA) raid the building and arrest Delphi’s leader. The HOA, replicates the Healing Touch, using data collected from Dr. Stiles and some other unknown method in order to give their own surgeons the same power. Though the mysterious procedure is successful, many of the other chraracters become wary of the artificially enhanced surgeons, as the latter group tend to appear too intense and emotionless.

Several days later, Angie’s father, who works for the HOA, informs the head of Caduceus that many of the HOA’s doctors are showing symptoms of GUILT. A police raid of Acropolis, a pharmaceuticals company working with the HOA, shows that the head of the HOA, Patrick Mercer, has been creating four new strains of GUILT, dubbed Neo-GUILT, hoping that one strain could cure his wife, who is in a coma. The Neo-GUILT were developed to be performance enhancers, explaining how the HOA was able to, at least temporarily, provide the Healing Touch, to any surgeon. Mercer tries to escape to another facility; Derek and Angie eventually follow Mercer into a room in which the head of Acropolis, Reina Mayuzumi, is attached to a series of tanks. She explains that she is using the last unknown Neo-GUILT strain to maintain her youth. Mercer injects her with a catalyst to see if the final Neo-GUILT is a performance enhancer strong enough to break comas, as the first three have already been proven as failures. Instead, the activated Neo-GUILT causes Mayuzumi to age rapidly, and necessitates a final surgery by Stiles. Mercer is shot by police while trying to escape. With the threat of GUILT neutralized, Derek and Angie begin to travel the world together to improve their skills, as well as to spend time together in their now budding romantic relationship.


The game's music is composed by Manabu Namiki and Noriyuki Kamikura.[3]

After completing the story mode in any difficulty, the player will unlock the Sound Test, where they can listen to the game's 18 tracks, as well as the game's sound effects and voice-overs.


Aggregate scores
Aggregator Score
GameRankings 81% (28 reviews)[4]
Metacritic 79% (29 reviews)[5]
Review scores
Publication Score B[6]
AllGame 3.5/5 stars[7]
Edge 6/10[8]
Game Informer 8.5/10[9]
GamePro 2.5/5 stars[10]
GameSpot 8.5/10[11]
GameSpy 4.5/5 stars[12]
GamesRadar+ 4/5 stars[13]
GameTrailers 7.8/10[14]
GameZone 8.5/10[15]
IGN 8.4/10[16]
Nintendo Power 8.5/10
Nintendo World Report 6.5/10
X-Play 4/5 stars[17]

Reception of Under the Knife 2 has been generally positive, with a 79% on Metacritic[5] and an 81% on GameRankings.[4] Edge rated Under the Knife 2 at 6/10, praising the visuals and controls, while criticising the lack of originality as compared to the first game.[8] It was nominated for Best Action Game on the DS in IGN's 2008 video game awards.[18]


  1. ^ Known in Japan as Kyūkyū Kyūmei Kadukeusu 2 (救急救命 カドゥケウス2, lit. Medical Emergency: Caduceus 2)


  1. ^ "IGN - Trauma Center: Under the Knife 2". IGN. Retrieved 2009-02-11. 
  2. ^ "GameSpot - Release Summary". GameSpot. Retrieved 2009-02-11. 
  3. ^ "Manabu Namiki Scores Trauma Center: Under the Knife 2". 2008-05-12. Archived from the original on 2008-05-22. Retrieved 2008-05-12. 
  4. ^ a b "Trauma Center: Under the Knife 2 Reviews". 
  5. ^ a b "Trauma Center: Under the Knife 2 (ds: 2008): Reviews". 
  6. ^ Fitch, Andrew (2008-07-01). "Trauma Center: Under the Knife 2 Review". Retrieved 2009-03-25. 
  7. ^ "Trauma Center: Under the Knife 2 Overview". Allgame. Retrieved 2009-03-25. 
  8. ^ a b Edge, November 2008, p102
  9. ^ "Trauma Center: Under the Knife 2". Game Informer. August 2008. Archived from the original on July 31, 2008. Retrieved 2009-03-25. 
  10. ^ Moore, Raychul (2008-07-17). "Review: Trauma Center: Under the Knife 2". GamePro. Archived from the original on 2008-08-27. Retrieved 2009-03-25. 
  11. ^ Stella, Shiva (2008-07-01). "Trauma Center: Under the Knife 2 Review for DS". GameSpot. Retrieved 2009-03-25. 
  12. ^ "GameSpy: Trauma Center: Under the Knife 2 Review". GameSpy. Retrieved 2009-03-25. 
  13. ^ Kim, Alan. "Trauma Center: Under the Knife 2 Review". GamesRadar. Retrieved 2009-03-25. 
  14. ^ "Trauma Center: Under the Knife 2 - Review". GameTrailers. August 7, 2008. Retrieved 2009-03-25. 
  15. ^ Hopper, Steven (2008-06-30). "Trauma Center: Under the Knife 2 Review". GameZone. Archived from the original on 2013-01-23. Retrieved 2009-03-25. 
  16. ^ "Trauma Center: Under the Knife 2 Review". IGN. June 27, 2008. Retrieved 2009-03-25. 
  17. ^ "Review: Trauma Center: Under the Knife 2". X-Play. Retrieved 2009-03-25. 
  18. ^ "IGN DS: Best Action Game 2008". 2008-12-15. Retrieved 2008-12-19. 

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