Meeks was born on April 27, 1979 in Charlestown, Indiana. His parents divorced when he was 2 and lived with his grandmother and father. At a young age he began playing guitar and wrote songs and performed covers by age 8. Between ages 11 to 15, he went to various rehabilitation centers and a year in special schooling. During that time he formed an experimental rock band called Bad Dreemz which included Jesse Vest and Matt Taul. They then formed Dead Reckoning, which was a heavy metal band that sounded similar to Pantera. In 1995, Meeks moved to Louisville and Dead Reckoning changed its name to Days of the New as well as its genre to an acoustic rock, post-grunge style. Regarding that era, Meeks stated, "I went through paranoia and acid trips, separation from the mind and body... That's where my spiritual journey begins."
At the age of 17, Meeks and fellow teenage band members Matt Taul, Todd Whitener and Jesse Vest were signed to a major record label. In 1997, they released their widely successful self-titled Yellow album that included the single, "Touch, Peel and Stand." The song rose to #1 on the Billboard charts and became the group's signature piece. Opening slots on tour with Jerry Cantrell and Metallica further exposed the band to fans around the country. Days of the New then set out on a headlining tour that lasted until a stop in Dallas, Texas when Meeks' father finally drove him home and canceled the remainder of the tour's shows.
Meeks has standing invitations to perform at the Ryman Auditorium in Nashville, as well as to front the Boston Pops. Recently, he has begun referring to himself as a maestro due to his self-taught mastery of the acoustic guitar and incorporation of classical sounds into his music.
In April 2005, Meeks was showcased in an episode of A&E's hit TV series Intervention, which was filmed in February that year. Meeks' addiction to methamphetamines was one of the two subjects for this episode. He decided to go to rehab at Cirque Lodge in Provo, Utah, but the episode ends with Meeks checking out early after 73 days. After a period of relapsing, he remained sober since September 19, 2005 until a brief relapse in September 2007. According to a follow-up interview with Intervention, Meeks has since remained sober.
On April 25, 2008, an interview with Meeks was featured on the podcast series, Uncensored Net Noise.
Meeks also has two daughters from previous relationships. His first daughter was born ca.1994 from his relationship with his then girlfriend Amy.
"Acoustic guitars are more musical. They're not all covered up by different sounds and distortions and stuff. Of course we put distortion on our guitars, but I like to go make campfires and sit out by the water, and you can't do that with an electric guitar. Each acoustic guitar has its own soul; it seems way more natural to play than electric."