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Systematic (IUPAC) name
(2S,3S)-2,3-Dihydroxybutane-1,4-diyl dimethanesulfonate
Clinical data
AHFS/ International Drug Names
Routes of
Oral, IV
CAS Registry Number 299-75-2 N
ATC code L01AB02
PubChem CID: 9296
Synonyms 1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate, Threitol 1,4-dimethanesulfonate, Threitol 1,4-bismethanesulfonate; L-Threitol 1,4-bis(methanesulfonate); Ovastat; Threosulphan; Treosulphan; Tresulfan
Chemical data
Formula C6H14O8S2
Molecular mass 278.30056 g·mol−1
 N (what is this?)  (verify)

Treosulfan is a substance that is being studied in the treatment of cancer.[1] It belongs to the family of drugs called alkylating agents. It has been used mainly as a substitute of busulfan in frail patients, as the side effects and toxicity are supposedly less severe.


  1. ^ Schmittel A, Schmidt-Hieber M, Martus P et al. (December 2006). "A randomized phase II trial of gemcitabine plus treosulfan versus treosulfan alone in patients with metastatic uveal melanoma". Ann. Oncol. 17 (12): 1826–9. doi:10.1093/annonc/mdl309. PMID 16971664. 

External links[edit]

  • Treosulfan entry in the public domain NCI Dictionary of Cancer Terms

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".