Treponema denticola

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Treponema denticola
Scientific classification e
Domain: Bacteria
Phylum: Spirochaetes
Order: Spirochaetales
Family: Spirochaetaceae
Genus: Treponema
Species: T. denticola

Treponema denticola is a Gram-negative, obligate anaerobic, motile and highly proteolytic spirochete bacterium. It dwells in a complex and diverse microbial community within the oral cavity and is highly specialized to survive in this environment. T. denticola is associated with the incidence and severity of human periodontal disease. Having elevated T. denticola levels in the mouth is considered one of the main etiological agents of periodontitis.[1] T. denticola is related to the syphilis-causing obligate human pathogen, Treponema pallidum subsp. pallidum. It has also been isolated from women with bacterial vaginosis.[2]

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  1. ^ Marie-Claude Jobin, Mohsen Amin, Richard P. Ellen (2008). "Chapter 8 - The Molecular Biology of the Survival and Virulence of Treponema denticola". In Anthony H. Rogers. Molecular Oral Microbiology. Caister Academic Press. p. 177. ISBN 978-1-904455-24-0. 
  2. ^ Africa, Charlene; Nel, Janske; Stemmet, Megan (2014). "Anaerobes and Bacterial Vaginosis in Pregnancy: Virulence Factors Contributing to Vaginal Colonisation". International Journal of Environmental Research and Public Health. 11 (7): 6979–7000. doi:10.3390/ijerph110706979. ISSN 1660-4601. PMC 4113856Freely accessible. PMID 25014248. 

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