Troxerutin

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Troxerutin
Troxerutin.svg
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
Synonyms Hydroxyethylrutoside (HER)
Pherarutin
Trihydroxyethylrutin
3',4',7-Tris[O-(2-hydroxyethyl)]rutin
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
Formula C33H42O19
Molar mass 742.67518 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Troxerutin is a flavonol, a type of flavonoid. It is more accurately a hydroxyethylrutoside. It can be isolated from Sophora japonica, the Japanese pagoda tree.

It is used as a vasoprotective.[1]

Troxerutin has been shown in mice to reverse CNS insulin resistance and reduce reactive oxygen species induced by a high-cholesterol diet.[2]

References[edit]

  1. ^ Riccioni, C.; Sarcinella, R.; Izzo, A.; Palermo, G.; Liguori, M. (2004). "Effectiveness of Troxerutin in association with Pycnogenol in the pharmacological treatment of venous insufficiency". Minerva cardioangiologica. 52 (1): 43–48. PMID 14765037. 
  2. ^ Lu, J.; Wu, D. -M.; Zheng, Z. -H.; Zheng, Y. -L.; Hu, B.; Zhang, Z. -F. (2011). "Troxerutin protects against high cholesterol-induced cognitive deficits in mice". Brain. 134 (3): 783–797. doi:10.1093/brain/awq376. PMID 21252113.