Truncal neural crest

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Truncal neural crest
Latin crista neuralis truncalis
TE E5.
Anatomical terminology

The truncal neural crest or trunk neural crest is a form of neural crest.[1]

The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia

Other Migration Locations:

Differentiation involves BMP/noggin.[4]


  1. ^ "The Neural Crest". Retrieved 2009-05-31. 
  2. ^ Lacosta AM, Muniesa P, Ruberte J, Sarasa M, Domínguez L (August 2005). "Novel expression patterns of Pax3/Pax7 in early trunk neural crest and its melanocyte and non-melanocyte lineages in amniote embryos". Pigment Cell Res. 18 (4): 243–51. doi:10.1111/j.1600-0749.2005.00238.x. PMID 16029418. 
  3. ^ Lallier TE (1991). "Cell lineage and cell migration in the neural crest". Ann. N. Y. Acad. Sci. 615: 158–71. doi:10.1111/j.1749-6632.1991.tb37758.x. PMID 2039141. 
  4. ^ Burstyn-Cohen T, Stanleigh J, Sela-Donenfeld D, Kalcheim C (November 2004). "Canonical Wnt activity regulates trunk neural crest delamination linking BMP/noggin signaling with G1/S transition". Development. 131 (21): 5327–39. doi:10.1242/dev.01424. PMID 15456730.