Tryptase is also known by mast cell tryptase, mast cell protease II, skin tryptase, lung tryptase, pituitary tryptase, mast cell neutral proteinase, mast cell neutral proteinase, mast cell serine proteinase II, mast cell proteinase II, mast cell serine proteinase tryptase, rat mast cell protease II, and tryptase M.
Serum levels are normally less than 11.5 ng/mL. Elevated levels of serum tryptase occur in both anaphylactic and anaphylactoid reactions, but a negative test does not exclude anaphylaxis. Tryptase is less likely to be elevated in food allergy reactions as opposed to other causes of anaphylaxis.
^Kido H, Fukusen N, Katunuma N (1985). "Chymotrypsin- and trypsin-type serine proteases in rat mast cells: properties and functions". Arch. Biochem. Biophys239: 436–443. doi:10.1016/0003-9861(85)90709-X. PMID3890754.
^Cromlish JA, Seidah NG, Marcinkiewicz M, Hamelin J, Johnson DA, Chrétien M (1987). "Human pituitary tryptase: molecular forms, NH2-terminal sequence, immunocytochemical localization, and specificity with prohormone and fluorogenic substrates". J. Biol. Chem.262: 1363–1373. PMID3543004.
^Harvima IT, Schechter NM, Harvima RJ, Fräki JE (1988). "Human skin tryptase: purification, partial characterization and comparison with human lung tryptase". Biochim. Biophys. Acta957: 71–80. doi:10.1016/0167-4838(88)90158-6. PMID3140898.