Group V ((−)ssRNA)
|Tupavirus||Durham tupavirus*||Durham virus (DURV)|
|Tupaia tupavirus||tupaia virus (TUPV)|
Table legend: "*" denotes type species.
Tupavirions enveloped, with bullet shaped geometries. These particles are about 160 nm long. Tupavirus genomes are linear, around 11.2 kb in length. The genome codes for 7 proteins.
|Genus||Structure||Symmetry||Capsid||Genomic arrangement||Genomic segmentation|
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral G glycoproteins to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. The virus exits the host cell by budding, and tubule-guided viral movement. Birds serve as the natural host for Durham tupavirus, with antibodies having been found in the American Coot (Fulica americana). Additionally, antibodies for Klamath tupavirus have been found in several species of deer, bison, and humans., as well as voles and shrews.
|Genus||Host details||Tissue tropism||Entry details||Release details||Replication site||Assembly site||Transmission|
- "Viral Zone". ExPASy. Retrieved 13 August 2015.
- ICTV. "Virus Taxonomy: 2014 Release". Retrieved 13 August 2015.
- Afonso, Claudio L.; Amarasinghe, Gaya K.; Bányai, Krisztián; Bào, Yīmíng; Basler, Christopher F.; Bavari, Sina; Bejerman, Nicolás; Blasdell, Kim R.; Briand, François-Xavier (1 August 2016). "Taxonomy of the order Mononegavirales: update 2016". Archives of Virology. 161 (8): 2351–2360. doi:10.1007/s00705-016-2880-1. ISSN 1432-8798. PMC 4947412. PMID 27216929.
- ICTV. "Genus: Tupavirus". Retrieved 12 August 2019.