Twentymile Creek is considered the largest stream on the eastern portion of the City of Erie. It is stocked annually with steelhead and trout by the Pennsylvania Fish Commission. Twentymile Creek is an approved trout water, so its fishing can be good throughout the year. Steelhead run into Twentymile all the way to New York, but not many anglers venture up that far to fish. New York State has undertaken efforts to stock brown trout in the upper reaches of Twentymile as well. The brown trout migrate out into Lake Erie and return to spawn. Access points along Route 20 are posted.