Tyrosine-protein kinase BLK

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BLK
Identifiers
Aliases BLK, MODY11, BLK proto-oncogene, Src family tyrosine kinase
External IDs MGI: 88169 HomoloGene: 1297 GeneCards: 640
Genetically Related Diseases
Disease Name References
smallpox
Rheumatoid Arthritis
systemic lupus erythematosus
RNA expression pattern
PBB GE BLK 206255 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001715

NM_007549

RefSeq (protein)

NP_001706.2

NP_031575.2

Location (UCSC) Chr 8: 11.49 – 11.56 Mb Chr 14: 63.37 – 63.42 Mb
PubMed search [4] [5]
Wikidata
View/Edit Human View/Edit Mouse

Tyrosine-protein kinase BLK also known as B lymphocyte kinase is an enzyme that in humans is encoded by the BLK gene.[1][2]


Interactions[edit]

The tyrosine-protein kinase BLK has been shown to interact with UBE3A.[3]

References[edit]

  1. ^ Drebin JA, Hartzell SW, Griffin C, Campbell MJ, Niederhuber JE (Mar 1995). "Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk)". Oncogene 10 (3): 477–86. PMID 7845672. 
  2. ^ "Entrez Gene: BLK B lymphoid tyrosine kinase". 
  3. ^ Oda H, Kumar S, Howley PM (August 1999). "Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination". Proc. Natl. Acad. Sci. U.S.A. 96 (17): 9557–62. doi:10.1073/pnas.96.17.9557. PMC 22247. PMID 10449731. 

Further reading[edit]