Tyrosine-protein kinase BLK

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BLK
Identifiers
Aliases BLK, MODY11, BLK proto-oncogene, Src family tyrosine kinase
External IDs MGI: 88169 HomoloGene: 1297 GeneCards: BLK
Gene location (Human)
Chromosome 8 (human)
Chr. Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for BLK
Genomic location for BLK
Band 8p23.1 Start 11,494,001 bp[1]
End 11,564,604 bp[1]
RNA expression pattern
PBB GE BLK 206255 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001715
NM_001330465

NM_007549

RefSeq (protein)

NP_001317394
NP_001706

NP_031575

Location (UCSC) Chr 8: 11.49 – 11.56 Mb Chr 8: 63.37 – 63.42 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tyrosine-protein kinase BLK also known as B lymphocyte kinase is an enzyme that in humans is encoded by the BLK gene.[5][6]


Interactions[edit]

The tyrosine-protein kinase BLK has been shown to interact with UBE3A.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000136573 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000014453 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Drebin JA, Hartzell SW, Griffin C, Campbell MJ, Niederhuber JE (Mar 1995). "Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk)". Oncogene. 10 (3): 477–86. PMID 7845672. 
  6. ^ "Entrez Gene: BLK B lymphoid tyrosine kinase". 
  7. ^ Oda H, Kumar S, Howley PM (August 1999). "Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination". Proc. Natl. Acad. Sci. U.S.A. 96 (17): 9557–62. doi:10.1073/pnas.96.17.9557. PMC 22247Freely accessible. PMID 10449731. 

Further reading[edit]