U.S. Route 151 Business is designated along the former alignment of U.S. Route 151 through Cedar Rapids and Marion, Iowa. US 151 Business begins at exit 248, the intersection of US 30 / US 218 and US 151 in Cedar Rapids. US 151 Business follows Williams Boulevard northeast to 1st Avenue, which it follows for the rest of its path through Cedar Rapids. 1st Avenue becomes Marion Boulevard in Marion. US 151 Business follows 7th Avenue to its northern terminus, the intersection of US 151 and Iowa Highway 13.
US 151 Bus. runs along 1st Avenue in downtown Cedar Rapids
U.S. Route 151 Business in Monticello was created in 2004 when US 151 was expanded and rerouted around Monticello. US 151 Business in Monticello begins at exit 68 of U.S. Route 151. It is co-signed with Jones County Route X44 until the Monticello city limits. In Monticello, US 151 Business follows Main Street. Between Oak Street and 1st Street, Iowa Highway 38 overlaps US 151 Business. The northern terminus of US 151 Business is an at-grade intersection with US 151.
Business U.S. Highway 151 (Bus. US 151) is a business route of U.S. Highway 151 (US 151) in Mineral Point, Wisconsin that is 3.7 miles (6.0 km) long. When it starts at US 151 outside of Mineral Point, it is concurrent with County Trunk Highway O. The concurrency is very short, and ends just after it starts. Inside Mineral Point, the route becomes concurrent with Wisconsin Highway 39. After this concurrency ends, it becomes concurrent with Wisconsin Highway 23. It then heads towards US 151 and ends there, intersecting County Trunk Highway YD along the way.