UBE2G1

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UBE2G1
Protein UBE2G1 PDB 2awf.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases UBE2G1, E217K, UBC7, UBE2G, ubiquitin conjugating enzyme E2 G1
External IDs MGI: 1914378 HomoloGene: 2508 GeneCards: 7326
RNA expression pattern
PBB GE UBE2G1 209141 at tn.png

PBB GE UBE2G1 209142 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_182682
NM_003342

NM_025985

RefSeq (protein)

NP_003333.1

NP_080261.2

Location (UCSC) Chr 17: 4.27 – 4.37 Mb Chr 11: 72.61 – 72.69 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Ubiquitin-conjugating enzyme E2 G1 is a protein that in humans is encoded by the UBE2G1 gene.[1][2]

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins.[2]

References[edit]

  1. ^ Watanabe TK, Kawai A, Fujiwara T, Maekawa H, Hirai Y, Nakamura Y, Takahashi E (Dec 1996). "Molecular cloning of UBE2G, encoding a human skeletal muscle-specific ubiquitin-conjugating enzyme homologous to UBC7 of C. elegans". Cytogenet Cell Genet 74 (1–2): 146–8. doi:10.1159/000134403. PMID 8893823. 
  2. ^ a b "Entrez Gene: UBE2G1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)". 

Further reading[edit]