Ubiquitin carboxyl-terminal hydrolase L5

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Protein UCHL5 PDB 3A7S.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases UCHL5, CGI-70, INO80R, UCH-L5, UCH37, Ubiquitin carboxyl-terminal hydrolase L5, ubiquitin C-terminal hydrolase L5
External IDs MGI: 1914848 HomoloGene: 9326 GeneCards: UCHL5
Gene location (Human)
Chromosome 1 (human)
Chr. Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for UCHL5
Genomic location for UCHL5
Band 1q31.2 Start 193,012,250 bp[1]
End 193,060,080 bp[1]
RNA expression pattern
PBB GE UCHL5 220083 x at fs.png

PBB GE UCHL5 219960 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)


RefSeq (protein)


Location (UCSC) Chr 1: 193.01 – 193.06 Mb Chr 1: 143.78 – 143.81 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase isozyme L5 is an enzyme that in humans is encoded by the UCHL5 gene.[5][6][7]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116750 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018189 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876Freely accessible. PMID 10810093. 
  6. ^ Wicks SJ, Haros K, Maillard M, Song L, Cohen RE, Dijke PT, Chantry A (Dec 2005). "The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling". Oncogene. 24 (54): 8080–4. doi:10.1038/sj.onc.1208944. PMID 16027725. 
  7. ^ "Entrez Gene: UCHL5 ubiquitin carboxyl-terminal hydrolase L5". 

Further reading[edit]