UPK3A

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UPK3A
Identifiers
AliasesUPK3A, UP3A, UPIII, UPIIIA, UPK3, uroplakin 3A
External IDsMGI: 98914 HomoloGene: 5066 GeneCards: UPK3A
Gene location (Human)
Chromosome 22 (human)
Chr.Chromosome 22 (human)[1]
Chromosome 22 (human)
Genomic location for UPK3A
Genomic location for UPK3A
Band22q13.31Start45,284,982 bp[1]
End45,295,874 bp[1]
RNA expression pattern
PBB GE UPK3A 206771 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001167574
NM_006953

NM_023478

RefSeq (protein)

NP_001161046
NP_008884

NP_075967

Location (UCSC)Chr 22: 45.28 – 45.3 MbChr 15: 85.02 – 85.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Uroplakin-3a is a protein that in humans is encoded by the UPK3A gene.[5][6] It is found in the inner membrane of the urinary bladder and contributes to the strength of that membrane and to the membrane's ability to stretch when the bladder is full.[7] It is also found in the renal pelvis, ureter, and prostatic urethra.


References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100373 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022435 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Yuasa T, Yoshiki T, Tanaka T, Kim CJ, Isono T, Okada Y (Dec 1998). "Expression of uroplakin Ib and uroplakin III genes in tissues and peripheral blood of patients with transitional cell carcinoma". Jpn J Cancer Res. 89 (9): 879–82. doi:10.1111/j.1349-7006.1998.tb00643.x. PMID 9818021.
  6. ^ "Entrez Gene: UPK3A uroplakin 3A".
  7. ^ Wu XR, Kong XP, Pellicer A, Kreibich G, Sun TT (2009). "Uroplakins in urothelial biology, function, and disease". Kidney Int. 75: 1153–65. doi:10.1038/ki.2009.73. PMC 3717210. PMID 19340092.

Further reading[edit]